Antimicrobial Resistance Centre

Inspiring innovation in AMR research through interdisciplinary and international engagements.

About the Antimicrobial Resistance (AMR) Centre

AMR is a threat to life and healthcare globally. With increasing levels of international concern about AMR, we need high quality research and evidence to guide action. The London School of Hygiene & Tropical Medicine is unique in the breadth of disciplines used to meet this complex challenge. These range from microbiology and clinical medicine to social studies and economics. The School’s Antimicrobial Resistance Centre, launched in 2016, will foster connections between these scientific approaches, generating innovative approaches to science and policy.

The Centre is based on five disciplinary pillars:

The aims of the AMR Centre are:

  1. Promote and facilitate high quality research into AMR that builds on and exploits disciplinary strengths across LSHTM.
  2. Facilitate AMR related funding responses and collaboration opportunities.
  3. Provide an interface for LSHTM’s AMR research for staff, public, press and wider research communities.
  4. Provide educational materials on AMR.

Talk | Global efforts to build AMR surveillance in low resource settings, examples from the Fleming Fund

A brief overview of the UK government’s international policy on AMR and its efforts to tackle AMR globally. Join this talk on 17 Jul, 5.30pm at Manson Lecture Theatre.

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Can active case detection help to eliminate multidrug resistant malaria in Cambodia?

The spread of resistance of P. falciparum malaria parasites to artemisinins is one of the biggest threats to global malaria control and elimination, and has the potential to result in millions of deaths, mainly in African children.    Cambodia, which is at the epicentre of antimalarial drug resistant malaria, declared a goal of eliminating malaria by 2025.  However there are lots of questions about how to achieve this operationally.

Watch the video

Spotlight 09/07/2018 Antibiotic innovation: coming home?

Imagine we have a time machine to take us back to the wondrous 1960s. It was a time when England won its first World Cup, and most importantly, the peak of the ‘golden age’ of antibiotic discovery. By then, more than 20 new classes of antibiotics were marketed [1] and about a half of the drugs commonly used today were discovered [2]. This phase of rapid pipeline expansion and mass production was made possible by the collective efforts of scientists, governments and pharmaceutical companies across the United Kingdom and the United States [3]. In short, it was a time when football came home [4] and antibiotic innovation was well at home.

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Metrics and Methods for Assessing Antibiotic Use – Roundtable

In late November 2017, the AMR Centre hosted 38 researchers, health and policy professionals in London for a roundtable to discuss how best antibiotic use can be measured in a way that informs strategies to address antibiotic resistance both nationally and internationally.

Read about the roundtable discussion here.

AMR resources

ABU on Farms
The AACTING Consortium has published Guidelines for the collection, analysis and reporting of farm-level antimicrobial use, in the scope of antimicrobial stewardship.
Stewardship Book
BSAC has published a new free e-book on Antimicrobial Stewardship. The book “provides a GLOBAL and highly PRACTICAL primer on the wise use of ANTIBIOTICS by applying the principles of stewardship to a wide range of professions, populations, and clinical/care settings”

VIDEO | Rise and fall of the magic bullet

AMR Centre member Sam Willcocks walks us through the rise and fall of antibiotics, and shows us why we need to think carefully about how we harness new technology so that we can continue to do good.