Project

AMR Education Challenge Contest

AMR Education Challenge Contest Antimicrobial resistance (AMR) is a major concern in healthcare today. The continuous misuse of antibiotics contributes significantly to this problem. This reduces the efficacy of antibiotics, limits treatment options, and places a serious burden on healthcare systems across the world. Development of new antibiotic drugs is dwindling with increasing rates of […]

A randomised experiment exploring antibiotic prescribing practices among private health facilities in Tanzania

This study, embedded in a wider evaluation of quality of care in private health facilities in Tanzania, aims to identify the role of patient knowledge and provider driven demand in over-prescription of antibiotics. Tackling the irrational use of antibiotics in outpatient settings is seen as a cornerstone of the global fight against AMR, but the drivers of […]

Antibiotic Prescribing and Resistance: Views from LMIC Prescribing and Dispensing Professionals

Principal Investigator: Clare Chandler, LSHTM Funder: World Health Organisation Dates: 2017-2018 Background The resistance of bacteria to an increasing array of antibiotic drugs is a cause of international concern. The widespread use of antibiotics is held responsible to a large extent for the development of drug-resistant strains of infection. In LMICs, this is of particular […]

Anti-Microbials In Society (AMIS): a Global Interdisciplinary Research Hub

Public Health and Policy Clare Chandler ESRC, 2017-2021 The Anti-Microbials In Society (AMIS) Programme Antimicrobial resistance (AMR) is a potentially catastrophic global problem. Our use of antimicrobial drugs, including antibiotics, has escalated. These medicines are now a routine part of everyday life. For example, we use antibiotics not only to cure infections but in anticipation […]

Personalised Risk assessment in febrile illness to optimise Real-life Management across the European Union (PERFORM)

Clinical & Veterinary Sciences; Economic, Social & Political Sciences LSHTM PI and Workpackage 5 lead: Shunmay Yeung Other LSHTM co-investigators:  Martin Hibberd, Alec Miners Consortium Co-ordinator: Michael Levin (Imperial College) Funding: European commission (Horizon 2020), 5 years Summary: PERFORM aims at developing new “omics” diagnostic tests to distinguish between bacterial and viral infections in febrile […]

Economic Evaluation support to a trial that assess strategies to address anti-microbial resistance in malnourished children (FLACSAM)

Investigators: Anna Vassall, Julie Jemutai (KEMRI-Wellcome Trust Research Programme) Funding: Joint Global Health Trials Scheme – DFID, Wellcome Trust Summary: An economic evaluatoin of first Line Antimicrobials in Children with Complicated Severe Acute Malnutrition. Children with complicated severe acute malnutrition (SAM) admitted to hospital in sub-Saharan Africa have a case fatality of 12% to more than 20%. Because children […]

How do policymaker perceptions of antimicrobial resistance drive behaviour and policies for appropriate antimicrobial use? A case study of Pakistan

Investigators: Jo Hanefeld, Mishal Khan, Helena Legido-Quigley (NUS), Ana Mateus (RVC), Rumina Hasan (Aga Khan University Pakistan) Funding: ESRC pump primer, 2017 Summary: This project focuses on the drivers of policy actor behaviour in one high risk AMR country in South Asia – Pakistan. With a population of 185 million, it is possibly the largest country without […]

Febrile Illness Evaluation in a Broad Range of Endemicities (FIEBRE)

Clinical & Veterinary Sciences; Economic, Social & Political Sciences Funding:  Department for International Development (DFID), 2017-2021 LSHTM investigators:  David Mabey (PI), Amit Bhasin, Chrissy Roberts, Clare Chandler, Heidi Hopkins, Coll Hutchison, John Bradley, Rashida Ferrand, Shunmay Yeung Other UK and international collaborators: Quique Bassat, Vilada Chansamouth, John Crump, Ethel Dauya, Nick Feasey, David Lalloo, Hla Hla […]