Spotlight 18/06/18 | FIEBRE launches first two study sites

The past few weeks, members of the FIEBRE study collaboration have been working together to begin study activities at the first two sites: Harare, Zimbabwe, with colleagues from the Biomedical Research and Training Institute (BRTI), and Chikwawa, Malawi, with the Malawi–Wellcome Trust team. FIEBRE’s primary objectives are to identify the leading infectious causes of fever […]

Spotlight 11/06/18 | Antibiotic resistance and local temperature

A recently-published letter to Nature Climate Change highlighted how crises produced by anthropogenic climate change and antimicrobial resistance might conceivably converge, redrawing geographies of resistance and treatment failure, and adducing potential correspondences with ecosystemic threats. The letter outlines the development of a database of antibiotic resistance patterns in the continental USA, relating to specific infection […]

Spotlight 04/06/18 | Antibiotics Supply is Failing to Meet Demand

The Access to Medicine Foundation has released a new White Paper calling for solutions to a failing antibiotic market. In the work, entitled “Shortages, stockouts and scarcity: the issues facing the security of antibiotic supply and the role for pharmaceutical companies”, they argue that antibiotic supply chains are “on the brink of collapse”, and detail […]

Spotlight 28/05/18 | Drugs, Bugs and our Precarious Existence

This weekend I had the privilege of engaging with Laura Piddock and Ed Whiting and members of the public at the Hay-on-Wye How The Light Gets In Festival. Angela Saini, health journalist, asked us whether it will be possible to defeat antimicrobial resistance, or whether we should come to terms with our precarious existence. I […]

Spotlight 21/05/18 | AMR in agriculture and a new list of essential diagnostic tests

This week has seen two important stories reach the internet – and I am not talking about Yanny/Laurel debate either. This was the highlighting of the problem of AMR in mycology and the release of the WHO list of essential diagnostic test. Rising anti-fungal resistance The recent paper in Science reviewed the problem of antifungal […]

Spotlight 15/05/18 | Mass administration of azithromycin: why, and why not?

Amongst intense attention on stimulating innovation and enforcing stewardship of antibiotics, a recent study—a cluster-randomised trial—highlights just how critical ensuring access to antibiotics is. Published in the New England Journal of Medicine, Keenan et al. reported the efficacy of mass administration of azithromycin, which is known to be effective in reducing rates of trachoma, malaria […]

Help develop engaging activities for the Bloomsbury Festival

The School has been invited to contribute to this year’s Bloomsbury Festival taking place from 17-21 October 2018, and we’d like to hear from you if you have any ideas for events or activities about the research we do or would like to take part. Bloomsbury Festival is a five-day celebration of the area’s pioneering […]

Spotlight 07/05/18 | TB and AMR seminar post World-TB day

I came in to the Rose Room one April lunchtime at LSHTM, alongside a handful of other students, to sacrifice a rare sighting of the sun in London for an insight in to AMR research. Though slightly sleep deprived from assignments, I was nonetheless upbeat to hear from leading researchers. The event organisers Chathika (Researcher, […]

Spotlight 23/04/18 | Successful treatment of “world’s worst” antibiotic resistant “super-gonorrhoea”

Late last week, Public Health England (PHE) reported that a UK man infected with the “world’s worst” antibiotic resistant “super-gonorrhoea” has been successfully treated. The case was initially announced by PHE in March, and widely publicized in the mainstream news media. The infection, contracted in southeast Asia, is resistant to both elements of the recommended […]

Spotlight 09/04/18 | Advice on the use of antibiotics to treat tuberculosis

‘Antimicrobial resistance’ is a useful term, but the readership of this newsletter does not need reminding that it is a broad term that somewhat oversimplifies the science. Clinically, ‘breakpoints’ are used to define a minimum inhibitory concentration above which a pathogen is susceptible to a given drug. However, this too is an over-simplification, because breakpoints […]