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Current newsletter

22 October 2018

This week’s AMR Centre Newsletter was compiled by James Cross, Student Representative (Overseas) the AMR Centre
 

 

Spotlight

Are you a PhD student at LSHTM? Do you want to be an active member of the management team for the AMR Centre at LSHTM? We currently require a new UK-based student representative to join our team! This is a voluntary position for current LSHTM PhD students and lasts until the end of the academic year. This is great opportunity to network and gain some experience in communications support, social media content generation, and event planning for your CV!

Please email James.Cross@lshtm.ac.uk for more information. Closing date for applications is on the 26th October 2018. Interviews will be held on the 6th November 2018 at LSHTM.

For more information please view our LSHTM Antimicrobial Resistance Centre Student Facebook Group: https://www.facebook.com/groups/LSHTMCentreofAMRStudentGroup/

 

 

External news

HSBC issues an alarming warning about antibiotic resistance
According to the global research team at HSBC, the use of antibiotics in meat production could have “devastating” consequences for humanity.

HP Deploying Printer to Test for Antibiotic Resistance
Hewlett-Packard (HP) and the Centers for Disease Control and Prevention (CDC) have announced a program installing HP printers as part of CDC’s Antibiotic Resistance Laboratory Network (AR Lab) that prints pharmaceuticals in order to speed up antibiotic testing.

New Test Instantly Identifies Antibiotic-Resistant Superbugs
University of California Berkeley researchers have created a new cheap test that can diagnose patients with antibiotic-resistant strains of bacteria in a couple of minutes.

 

 

Events at LSHTM

1 November, 09:00-18:00: International Diagnostics Centre and the AMR Centre at the London School of Hygiene & Tropical Medicine (LSHTM)
Title: Clinical Diagnostics and Antimicrobial Resistance: A multidisciplinary symposium
Venue: George Fox Room, Friends House 173-177 Euston Road London NW1 2BJ
Please sign up here

The AMR Centre lunchtime seminar series
AMR Centre seminars are usually on the first Tuesday of each month at 12.45pm. Please visit the events page of our website for more information.

Upcoming seminar:
6 November, 13.00pm: A lunchtime seminar with David Weber M.D. from UNC School of Medicine
Title: Demonstrating the role of the contaminated environment in transmission of healthcare-associated pathogens: new methods for terminal disinfection.
Venue: Weston Room (LG4), Tavistock Place

Missed a seminar?
Recordings of some of our past seminars can be accessed through the links below:

 

External events

Antimicrobial Resistance at The World Investment Forum: UNCTAD, WHO Join Forces
The World Investment Forum 2018, a biennial event organised by the United Nations Conference on Trade and Development (UNCTAD), will hold a session on health this year jointly with the World Health Organization. The session will address the need for investment in the development of new antibiotics, hoping to raise interest among investors.

World Anti-Microbial Resistance Congress 2018
Antimicrobial Resistance Congress is set to be the most strategic AMR conference globally. Get involved now to showcase your solutions to government authorities, pharma & biotech.
Start date: 25 October, 2018. End date: 26 October, 2018

 

Funding

Government provides £32m for innovative antimicrobial resistance research
The National Institute for Health Research is accepting applications for part of its open funding pot to support antimicrobial resistance research. Up to £32m of funding will be awarded to the NHS, universities and research organisations for research into antimicrobial resistance (AMR), the Department of Health and Social Care has announced. The government says the money will support capital investment into buildings and equipment, with the aim of fostering innovative approaches to tackling AMR. The funding will be managed by the National Institute for Health Research and will be awarded for a two-year period starting on 1 April 2019, with applications for funding open until 6 December 2018.

 

LSHTM featured publication

Patterns of Mutation Within An Emerging Endemic Lineage of HEV-3a
Zhu YO, Aw P, Aung MM, Lee HK, Hibberd M, Lee GH.
J Viral Hepat. 2018 Oct 13.

This week’s featured publication looks at viral mutations in hepatitis E virus. The hepatitis E virus can cause chronic infections in immuno-suppressed patients, and cases have been on the rise globally. Viral mutations during such infections are difficult to characterize. Zhu et al have deep sequenced viral populations from 15 immuno-compromised patients with chronic HEV to identify the viral lineage and describe viral mutational hotspots within and across patients.

External publications

Progress on antibiotic resistance
Editorial
Nature 562, 307 (2018)

The Changing Face of Water: A Dynamic Reflection of Antibiotic Resistance Across Landscapes.
Claire E. Sanderson, J. Tyler Fox, Eric R. Dougherty, Andrew D. S. Cameron, Kathleen A. Alexander.
Frontiers in Microbiology, 2018; 9

Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements.
Katariina Pärnänen, Antti Karkman, Jenni Hultman, Christina Lyra, Johan Bengtsson-Palme, D. G. Joakim Larsson, Samuli Rautava, Erika Isolauri, Seppo Salminen, Himanshu Kumar, Reetta Satokari, Marko Virta.
Nature Communications, 2018; 9 (1)

Antibiotic resistance in Palestine: an emerging part of a larger crisis.
Rupa Kanapathipillai, Nada Malou, Kate Baldwin, Pascale Marty, Camille Rodaix, Clair Mills,
Patrick Herard, Malika Saim.
BMJ 2018; 363

Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study.
Penny A. Asbell, Heleen H. DeCory.
PLOS, October 18, 2018

Development of a broad spectrum glycoconjugate vaccine to prevent wound and disseminated infections with Klebsiella pneumoniae and Pseudomonas aeruginosa.
Nicolas Hegerle, Myeongjin Choi, James Sinclair, Mohammed N. Amin, Morgane Ollivault-Shiflett, Brittany Curtis, Rachel S. Laufer, Surekha Shridhar, Jerod Brammer, Franklin R. Toapanta, Ian Alan Holder, Marcela F. Pasetti, Andrew Lees, Sharon M. Tennant, Alan S. Cross, Raphael Simon.
PLOS, September 6, 2018

Introduction and geographic availability of new antibiotics approved between 1999 and 2014.
Cecilia Kållberg , Christine Årdal, Hege Salvesen Blix, Eili Klein, Elena M. Martinez, Morten Lindbæk, Kevin Outterson, John-Arne Røttingen, Ramanan Laxminarayan.
PLOS, October 16, 2018

Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera.
Yue Wang, Ji Lu, Likai Mao, Jie Li, Zhiguo Yuan, Philip L. Bond & Jianhua Guo.
The ISME Journal (2018)

Developmental roadmap for antimicrobial susceptibility testing systems.
Alex van Belkum, Till T. Bachmann, Gerd Lüdke, Jan Gorm Lisby, Gunnar Kahlmeter, Allan Mohess, Karsten Becker, John P. Hays, Neil Woodford, Konstantinos Mitsakakis, Jacob Moran-Gilad, Jordi Vila, Harald Peter, John H. Rex, Wm. Michael Dunne Jr & the JPIAMR AMR-RDT Working Group on Antimicrobial Resistance and Rapid Diagnostic Testing.
Nature Reviews Microbiology (2018)

Submitting a grant application?

We’d love to hear from you

If you have applied for, or won, a grant award related to AMR research, please do let us know. We’d love to hear from you so that we can celebrate the hard work of our members. You can email us on: AMR@lshtm.ac.uk