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Current newsletter

19 – 25 February 2018

This week’s AMR Centre Newsletter was compiled by Henry Li, Economic, Social and Political Sciences Disciplinary Head.

Spotlight 

Book Your Place on the Our Short Course “AMR: A Multidisciplinary Approach”!

The one-week course, directed by Richard Stabler, with Clare Chandler and Sharon Peacock, is a collaboration of the AMR Centre at LSHTM with the University of Cambridge, and will run for the week of 16th July 2018. The course aims to equip delegates with the basic knowledge, conceptual frameworks and tools necessary to understand and respond to the complex threat of AMR. Focusing on each of the WHO’s Global Action Plan Objectives, participants will develop technical skills for planning and evaluating AMR programmes from a One Health perspective that incorporates multiple disciplines, multiple sectors and national and international level considerations.

Taught by international research leaders in AMR and disease control, the week will be kicked off by Baron Peter Piot and will include experts from The Wellcome Sanger Institute, the NHS as well as the LSHTM and University of Cambridge. Participants will engage with learning from hands-on laboratory work right through to social and economic analysis. As well as learning how to grow bacteria and test drug susceptibility on them in the lab, participants will visit Fleming’s laboratory in London, and will engage with the head of the Fleming Fund in an evening event.

The course responds to needs of those in positions of responsibility for AMR on national and international scales, for example those leading and implementing national action plans. The course fees have been fixed to be as low as possible in the hope of participation from delegates from low and middle income countries.

Check out course information and book your place online here

 

 

News: LSHTM 

Two drugs could potentially block malaria transmission new evidence suggests
An older malaria drug and a common laboratory dye with known antimalarial properties can safely and effectively be added to treatment regimens to block transmission of the most common form of malaria in Africa, according to a new study published in Lancet Infectious Diseases.
 

 

News: External

Happy Chinese Ne…isseria
In the run up to the Chinese New Year, a new study found high prevalence of drug resistance in Neisseria gonorrhoeae infections from the samples from nearly 4,000 patients from across China between 2013 and 2016, with almost 19% of cases being resistant to azithromycin, and almost 11% having reduced susceptibility to ceftriaxone. What’s more, the prevalence of concomitant resistance to azithromycin and decreased susceptibility to ceftriaxone increased from 1.9% to 3.3%. Considering these two antibiotics are the most important drugs against gonorrhoeae, and ceftriaxone is practically the last line of defence, this new finding should set alarm bells ringing.
Meanwhile, gonorrhoeae rides on a wave in Australia
Resistant gonorrhoeae is also surfacing in Australia. The latest report from the National Alert System for Critical Antimicrobial Resistance (CARAlert), which collects cases of critically resistant bacteria infection reported by 65 laboratories nationwide, found that a spike in the cases between April and September 2017 was significantly attributed to the almost tripling of resistant gonorrhoeae cases during this period, from 121 to 342. Alarm bells are turning into missile alerts.
At least a post-antibiotic apocalypse is not yet here…but wait
A world in which routine surgery cannot be performed due the lack of antibiotics that can prevent resistant postoperative infections is not merely some episode of Black Mirror. Analysing closed to 13,000 patients from 66 countries, a study by an international team found that 12% of the patients developed surgical site infections within a month of surgery, and 22% of the further tested patients had infections resistant to prophylactic antibiotics. Moreover, the prevalence of both the infections and the resistant infections disproportionately affects poorer countries. With antibiotic resistance continues to climb as the Year of the Dog begins, we have much to do to make sure antibiotics don’t go to the dogs.
 

 

Events: LSHTM

These seminars will be held at least on the first Tuesday of each month at 12:45.
Please visit the Events page on our website for more information.
This week:

Upcoming seminars:

Missed a seminar?

Recordings of some of our past seminars can be accessed through the links below:

Related events

  • 14 June 2018 – RESIST: LSHTM will be hosting a one-day workshop on the role of modelling in AMR. Gwen Knight, Katie Atkins, Laith Yakob and Nick Davies are finalising the programme; further details on speakers and how to sign up will be posted in near-future newsletters.
 

 

Events: External

19 February 2018. Soil: Exploring Tiny Things. ASCUS Lab, Summerhall Place, Edinburgh

21 February 2018. Innovation in the Microbiome by Innovation Forum London. B5 Auditorium, Franklin-Wilkins Building, London

6 March 2018. 2018 Jephcott Lecture – Professor Dame Sally Davies: the global challenge of drug resistant infections. Royal Society of Medicine

7–8 March 2018. Meeting of the Transatlantic Taskforce on AMR.

12–13 March 2018. BSAC Spring Conference 2018 – Progressing AMR: The trinity of prevention, preservation & promotion. Abstract submissions closed.

You can visit our website for further external events that you might find of interest.

 

Please note registration deadlines for the below:

28 March 2018. Biopollution: Antimicrobial Resistance in the Environment. This one-day symposium organised by the Environmental Chemistry Group of the Royal Society of Chemistry explores the chemistry and biochemistry of antimicrobial resistance in the environment, the policy relating to it and its effects on human health. The 2018 ECG Distinguished Guest Lecture will be provided by Professor Joakim Larsson (University of Gothenburg). You can register for the event on the RSC website – early registration until 28 February.

22–25 June 2018. 5th International OneHealth Conference. The 5th International One Health Congress is the world’s premier conference for the worldwide One Health community. Join the congress organizers, Prof. Ab Osterhaus and Prof. John Mackenzie, and One Health advocates from all over the globe in Saskatoon for four days of lectures, debates, workshops and symposia. Online abstract submission closes 15 February.

 

 

Student blog

To find out more about the Student blog or the team behind it, you can contact the AMR Centre Student Representative, James Cross.

This week’s student blog can be seen as the spotlight piece, written by Margarida Paixao (LSHTM AMR Centre Student Liaison Officer).

 

 

Featured publication

Vaccination to reduce antimicrobial resistance
Atkins KE, Flasche S.
Lancet Glob Health 2018; 6(3):e252. PubMedIn this Correspondence, Katherine Atkins and Stefan Flasche of LSHTM argue that mathematical modelling is essential in transfiguring recommendations of vaccine use to reduce AMR from banal propositions to concrete strategies.
 

 

Publications: LSHTM

Vaccination to reduce antimicrobial resistance
Atkins KEFlasche S.
Lancet Glob Health 2018; 6(3):e252. PubMed
Active Trachoma Cases in the Solomon Islands Have Varied Polymicrobial Community Structures but Do Not Associate with Individual Non-Chlamydial Pathogens of the Eye
Butcher RMR, Sokana O, Jack K, Kalae E, Sui L, Russell C, Houghton JPalmer CHolland MJ, Le Mesurier RT, Solomon AWMabey DCWRoberts CH.
Front Med (Lausanne) 2017; 4():251. PubMed

Please visit our website for a full list of publications.

 

 

Publications: External

Infectious Diseases Physicians: Leading the Way in Antimicrobial Stewardship
Ostrowsky B, Banerjee R, Bonomo RA, Cosgrove SE, Davidson L, Doron S, Gilbert DN, Jezek A, Lynch JB 3rd, Septimus EJ, Siddiqui J, Iovine NM.
Clin Infect Dis. 2018 Feb 12. PubMed

 

 

Funding opportunities

Wellcome ISSF/LSHTM Fellowships

We are pleased to announce the launch of the Wellcome Institutional Strategic Support Fund/LSHTM Fellowships. The School is seeking to appoint up to four LSHTM Fellows at the Assistant Professor level funded by the LSHTM and Wellcome ISSF. The LSHTM Fellowships aim to support the career progression of researchers at the mid-career transition, both internal and external applicants are eligible to apply.

These are open to experienced postdoctoral academics who are working towards toward applications for prestigious external mid-career fellowships to be based at the School. LSHTM Fellowships offer up to 18 months’ salary support, up to £10,000 flexible research funding and a place on the School’s Pathway to Academic Leadership Programme.

Full details of the fellowships and information on how to apply can be found in the jobs listing (ref: EPH-EPHC-2018-01).

Queries regarding the fellowships can be addressed to issf@lshtm.ac.uk. Please note that this scheme is administered by the Strategic Research Office. For this reason, we will be unable to provide the individual support usually offered for external funding bids.

Deadline: 26 February 2018

Fleming Fund Grants Programme Request for Proposals

The Fleming Fund has advertised Request for Proposals for grants to address critical gaps in surveillance of antibiotic resistant bacteria in Uganda, Ghana and Nepal. Mott MacDonald, the managing agent, invites proposals from qualified licensed/registered legal entities in each country to respond.

Please contact the Strategic Research Office for help and advice on applying for funding.

For further information on the above and other AMR funding schemes, see our website.

 

Submitting a grant application? We’d love to hear from you!

If you have applied for, or won, a grant award related to AMR research, please do let us know. We’d love to hear from you so that we can celebrate the hard work of our members.

 

 

Job opportunities

LSHTM
Research Assistant in Health Systems and Antimicrobial Resistance – Coordinate with local partners and lead field research on a new project entitled ‘Combating drug resistance through better governance of unregulated antimicrobial sellers in Cambodia: addressing stakeholder connections & perceptions’. Position to start as soon as possible.
IDDjobs

Job and PhD opportunities in the fields of transmission modelling, phylogenetics, pathogen ecology, epidemiology, and any topic broadly aligned with infectious disease dynamics are now gathered in one place at this new website. There are currently several opportunities at PhD and postdoc level focused on the spread of AMR.

Policy Officer on Antimicrobial Resistance, Wellcome Trust
Wellcome Trust is recruiting a Policy Officer to join the Drug Resistant Infections (DRI) team. In this role, you will to lead small projects (and strands of wider projects) to help develop and deliver key policy and advocacy elements of their global work on DRI. Application closes on 26th February.

Consultant Microbiologist, MSF International
MSF International is looking for a Consultant Microbiologist to join the Diagnostics Working Group for 6 months. The role will be based in Europe, starting March 2018. Please contact Dr Arlene Chua at Arlene.Chua@geneva.msf.org for more information.